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Evidence is increasing that every addiction without exception is related to difficulties with the brain's reward center, particularly the mesolimbic system. This area of the problem regulates reward responses in acquiring food and sex, plus in nurturing infants and children. One of the most important neurotransmitters involved with reward responses, both once they malfunction and after they function properly, is dopamine. What makes opiates unique is that it, among other neurotransmitters modulates "the quantity of dopamine released in in response to a stimulus"(Bostwick & Bucci, 2008).

Using two separate drugs to shed weight can be very effective you will find combinations before the FDA now awaiting approval. When dealing with weight-loss and the individuals who go through it you need to err to the side of caution and let the FDA do its job and demand some study be done so your public knows the side effects and dangers of the medications before we drive them. Keep in mind that drug companies have been in business to generate income and that they would say almost anything to keep people on his or her medications.

Researchers found out that participants taking this drug for any year, dropped excess weight within one month and have kept the body weight off through the 56 weeks in the study. Contrave is a combination of the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which can be made up of many active ingredient, which may make them more efficient and safer.

Combo-pilling is the newest fad or even better the newest ahead under scrutiny and therefore it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that by using a combination of pills is starting to become popular will be the fact that as of right now there aren't any long term prescription weight loss supplements that have been authorized by the FDA other than orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations have been rejected or have yet to be authorized by the FDA.

Seizures are a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug may also raise hypertension and pulse rate, and must not be used in those with a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure and heart rate and must 't be used in patients with uncontrolled high blood pressure levels, along with by you are not heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients using a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients towards the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking.

'The intent of this bill is usually to give police force and district attorneys a power tool to address illicit drug use among expectant women through treatment programs," Tennessee governor Bill Haslam said.

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