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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment selection for chronic weight management in addition to a reduced-calorie diet and exercise.

Using two separate drugs to lose weight can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it one should err to the side of caution and permit the FDA do its job and demand some study be done in order that the public knows the side effects and perils associated with the medications before we take them. Keep in mind that drug companies will be in business to generate money and that they would say almost anything to keep people on their own medications.

Researchers found that participants taking this drug for a year, dropped excess weight within four weeks and have kept the weight off throughout the 56 weeks in the study. Contrave can be a combination from the drugs naltrexone and bupropion, which appears to reflect a brand new trend of weight-loss drugs that are made up of multiple active ingredient, which might make them far better and safer.

Combo-pilling is the newest fad or in addition to this the newest in the future under scrutiny and thus it is just more publicly known although in the past, comb-pilling for weight loss has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular may be the fact that since right now there aren't any long term prescription weightloss pills that have been approved by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be approved by the FDA.

Seizures really are a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug can also raise blood pressure and heart rate, and mustn't be used in individuals with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with all the drug.

The FDA also warned that Contrave can raise blood pressure levels and pulse rate and must not be used in patients with uncontrolled high hypertension, as well as by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients which has a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients for the increased chance of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stop smoking.

'The intent of this bill would be to give law enforcement and district attorneys something to address illicit drug use among expectant women through treatment programs," Tennessee governor Bill Haslam said.

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